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Other recently suggested Nrf2 activators, such as the cell-permeable alkylating agent, dimethyl itaconate (Mills et al

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[9] Concomitant administration of large calcium supplements, thiazide diuretics, or aluminium-containing phosphate binders can potentiate vitamin D-mediated increases in serum calcium or phosphate, demanding periodic laboratory monitoring and dosage adjustments to avert nephrolithiasis or ectopic calcification